Cancer Genetic Services
UPMC CancerCenter cancer genetic services are coordinated through the Cancer Genetics Program (CGP), a joint program of UPMC, University of Pittsburgh Cancer Institute, and Magee-Womens Hospital of UPMC. The CGP provides education, research, and cancer risk assessment for individuals and their families who are concerned about their risk for cancer and how genetic inheritance may play a role.
CGP's genetic counselors are specially trained in cancer genetics and certified by the American Board of Medical Genetics or American Board of Genetic Counseling. CGP services include:
- Genetic counseling for determining cancer risk.
- Cancer screening and genetic testing education.
- Helps people and their families understand how certain cancers may cluster in families.
- Educates people on the most current and available genetic testing.
- Informs people about which cancer screening tests may offer early detection.
- Offers individualized prevention steps that make sense for each person.
Why do I need genetic counseling?
Many people undergo genetic consultation and, in specific cases, pursue targeted genetic testing for hereditary cancer syndromes, such as:
- Cowden Syndrome (PTEN)
- Familial Adenomatous Polyposis (APC)
- Familial Melanoma (CDKN2A)
- Hereditary Breast-Ovarian Cancer (BRCA1, BRCA2)
- Hereditary Non-polyposis Colorectal Cancer (MSH2, MLH1, MSH6, PMS2)
- Hereditary Paraganglioma (SDHB, SDHD)
- Li-Fraumeni Syndrome (TP53)
- Multiple Endocrine Neoplasia Type 1 (MEN1)
- Multiple Endocrine Neoplasia Type 2 (RET)
- Nevoid Basal Cell Carcinoma Syndrome (PTCH)
- Von Hippel-Lindau Disease (VHL)
What will I learn from genetic counseling?
Cancer risk consultation may relieve anxiety and provide a sense of control. After a complete review of your family and medical history, the consultation team will discuss the following information:
- Availability of genetic testing for certain cancers and the risks, benefits, and limitations of genetic testing.
- Cancer screening tests and recommendations for how often you should be screened.
- Complete analysis of your family tree.
- Estimation of your risks for specific cancers based upon your age, family history, and other risk factors.
- Possible role of genetics in your family's cancer and emotional issues surrounding cancer and risk.
Cancer Genetic Research and Continuing Medical Education (CME)
The CGP strives to provide expert clinical consultation in cancer genetics to develop a cohort of patients and families with hereditary cancer for a variety of research studies, and to provide training and CME for medical professionals.